منابع مشابه
tRNA-isoleucine-tryptophan composite gene.
Transfer-RNA genes in archaea often have introns intervening between exon sequences. The structural motif at the boundary between exon and intron is the bulge-helix-bulge. Computational investigations of these boundary structures in Haloarcula marismortui lead us to propose that tRNA-isoleucine and tRNA-tryptophan genes are co-located. Precise in silico identification of the splice-sites on the...
متن کاملNonprotein amino acid furanomycin, unlike isoleucine in chemical structure, is charged to isoleucine tRNA by isoleucyl-tRNA synthetase and incorporated into protein.
Nonprotein amino acid furanomycin was found to bind with Escherichia coli isoleucyl-tRNA synthetase (IleRS) almost as tightly as the substrate L-isoleucine. The conformation of furanomycin bound to the enzyme was determined by NMR analyses including the transferred nuclear Overhauser effect method. The conformation of IleRS-bound furanomycin was similar to that of L-isoleucine, although the che...
متن کاملA potato mitochondrial isoleucine tRNA is coded for by a mitochondrial gene possessing a methionine anticodon.
The nucleotide sequence of a potato mitochondrial tRNA(Ile) has been determined. This tRNA has a lysidine-like minor nucleotide in the first position of the anticodon (position 34). The corresponding mitochondrial gene has been cloned and sequenced. This gene has a CAT anticodon which corresponds to methionine. The C residue in the anticodon must therefore be post-transcriptionally modified. Th...
متن کاملEvolutionary constraints on the plastid tRNA set decoding methionine and isoleucine
The plastid (chloroplast) genomes of seed plants typically encode 30 tRNAs. Employing wobble and superwobble mechanisms, most codon boxes are read by only one or two tRNA species. The reduced set of plastid tRNAs follows the evolutionary trend of organellar genomes to shrink in size and coding capacity. A notable exception is the AUN codon box specifying methionine and isoleucine, which is deco...
متن کاملNucleotide sequence encoding genes for isoleucine- and alanine-accepting tRNA from Pseudomonas aeruginosa.
SEQUENCE AND ITS ORIGIN: Fragments of Pseudomonas aeruginosa (strain K, ATCC 25102) DNA encoding two tRNA genes have been seguenced as part of a project directed towards sequencing a complete ribosomal RNA operon from this organism. Clones from a BamHl library of P. aeruginosa DNA ligated into plasmid pOC9 were isolated by hybridisation with P. aeruginosa 16S and 23S ribosomal RNA molecules tha...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1994
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.14.6.3588